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I have been taking metformin 500 mg 2 x s daily for 17 months; my blood a1c was at 8.

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A serious allergic reaction is an emergencyContact a doctor straight away if you think you or someone around you is having a serious allergic reaction.

Feeling sicktake metformin with food to reduce the chances of feeling sickit may also help to slowly increase your dose over several weeks being sickvomitingor diarrhoeahave small but frequent sips of waterSpeak to a pharmacist if you have signs of dehydrationsuch as peeing less than usual or having darkstrong-smelling peeDon’t take any other medicines to treat diarrhoea or vomiting without speaking to a pharmacist or doctora metallic taste in the mouthif you find that metformin is giving you a metallic taste in the mouthtry chewing sugar-free gum.

Metformin stimulates ovulation in women with PCOS and can encourage regular periodseven if you don’t have diabetesIt does this by lowering insulin and blood sugar levelsPCOS can’t be cured but the symptoms can be managed.

Taking metformin with drugs used to treat glaucoma may increase your risk of lactic acidosisExamples of these drugs include:

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metformin hydrochloride did not cause adverse developmental effects when administered to pregnant sprague dawley rats and rabbits up to 600 mg kg day during the period of organogenesis.